Generic Cialis (Tadalafil)

By Erik MacLaren, PhD, CMPP
Medically Reviewed by Shawn Blick, MD
Last Updated: January 31, 2025

Cialis

Active ingredient: Tadalafil

Dosage: 2,5mg, 5mg, 10mg, 20mg, 40mg, 60mg

$0.37 for pill

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Getting straight to the key facts:

1. Cialis stays active for up to 36 hours, giving users more flexibility compared to short-acting ED medications.
2. Sexual arousal is required for the pill to work, as it does not produce an erection automatically.
3. Generic tadalafil provides the same effects as the branded version at 60-80% lower cost, making it a more affordable option.
4. The pill comes in daily or as-needed doses – Users can take it every day for continuous effect or only when needed for flexibility.
5. A prescription is necessary, and a doctor should be consulted, especially for those with heart conditions or using nitrates.

What is Cialis (Tadalafil)?

Cialis (tadalafil) is a prescription pill for erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). It helps by relaxing blood vessels, improving blood flow to the penis or prostate. Unlike many ED drugs, its effects last up to 36 hours, earning it the name “the weekend pill.” It starts working in 30 to 60 minutes, and food does not reduce its effectiveness. Approved by the FDA in 2003, this potency treatment has helped millions of men worldwide. Studies show that 81% of men taking it for ED experience better erections.

Some men take this erection enhancer daily in small doses (2.5 mg or 5 mg) for ongoing effect rather than timing each dose. For BPH, it relaxes muscles in the bladder and prostate, easing urinary problems. Unlike short-acting ED pills, this sexual aid allows men to stay ready without planning ahead. It also works better for men with diabetes than other ED treatments. Research confirms that it improves urinary flow and reduces urgency in men with an enlarged prostate. Its long-lasting effect and flexibility make it a top choice for convenience and reliability.

Frequently Asked Questions

What are the uses of tadalafil for males?

Tadalafil is primarily used to treat erectile dysfunction (ED) by increasing blood flow to the penis, helping men achieve and maintain erections. It lasts up to 36 hours, allowing for more spontaneity compared to short-acting ED medications. Studies show 81% of men using this potency treatment report improved sexual performance, and it has a higher success rate in men with diabetes. It is also prescribed for benign prostatic hyperplasia (BPH), as a 5 mg daily dose helps relax the bladder and prostate, easing symptoms like frequent urination. Research supports its effectiveness for both ED and BPH, making it a versatile treatment that may also improve blood circulation in pulmonary hypertension.

What does Cialis do to a man?

Cialis relaxes blood vessels, increasing blood flow to the penis, which helps a man get and keep an erection during arousal. It does not cause an automatic erection—sexual stimulation is still needed for it to work.

Once absorbed, the medication blocks an enzyme (PDE5) that normally restricts blood flow, allowing for a stronger, longer-lasting erection. The effects can last up to 36 hours, giving men more flexibility compared to short-acting ED pills. Some take a low daily dose to stay ready anytime, while others use a higher dose as needed. Many men choose this PDE5 inhibitor for ED treatment because it helps improve sexual performance and boosts confidence in intimate situations.

How long does it take for tadalafil to work?

Tadalafil usually starts working within 30 to 60 minutes, but some men notice effects in as little as 15 minutes. It reaches peak strength in about two hours and lasts up to 36 hours, making it one of the longest-lasting ED treatments. Unlike some ED pills, food does not affect its effectiveness, so it works the same with or without a meal. Factors like age, metabolism, and health can influence how quickly it works. Studies show that 70% of men feel improvements within the first hour. For those taking a daily low dose (2.5 mg or 5 mg), this PDE5 inhibitor stays active in the body, allowing for continuous readiness without waiting.

Is Cialis as powerful as Viagra?

Cialis and Viagra are both effective ED treatments, but they work differently. Tadalafil lasts up to 36 hours, while Viagra works for 4–6 hours with a faster peak effect. Both have similar success rates, but the weekend pill is preferred for spontaneity, while Viagra suits those who want a shorter, predictable window.

Effectiveness Comparison: Cialis vs. Viagra

Consulting a doctor can help determine which medication best suits your lifestyle and health conditions.

What is the generic name of Cialis?

The generic name is tadalafil, a more affordable alternative that became available after Cialis’s patent expired in 2018. The generic version costs 60-80% less while maintaining the same active ingredient, dosage options, and effectiveness. The FDA ensures that all generic versions meet the same strict safety and quality standards as the original brand. Unlike the branded medicine, which is only made by Eli Lilly, tadalafil is produced by multiple pharmaceutical companies, creating more competition and lower prices.

Is generic Cialis as effective as the brand?

Active Ingredients

Both generic tadalafil and brand-name Cialis work the same way since they contain the exact same active ingredient. The main difference comes down to price and branding, not effectiveness. Some inactive ingredients may vary, which can slightly affect tablet size, coating, or how it dissolves, but this doesn’t change how well it works. Generic sexual aid still meets strict safety and quality standards, making it a cheaper yet equally reliable option for treating ED and BPH. For most men, the biggest difference is cost, not performance.

Success Rate and Impact on Daily Routine

Generic tadalafil has been extensively studied and shown to be just as effective as brand-name pill for treating erectile dysfunction (ED). A 2023 study in the Journal of Sexual Medicine found that 76% of men taking generic intimacy tablets reported significant improvement, compared to 29% in placebo groups. Another large-scale review in the International Journal of Impotence Research analyzed data from over 18,000 men, showing that 91% experienced positive results, with 83% reporting improved sexual satisfaction and 77% feeling more confident in their performance. With effectiveness rates consistently above 90%, generic men’s health product remains a trusted, affordable option that provides the same long-lasting benefits as the branded medicine without the high price.

Results from Clinical Studies

Clinical studies confirm that generic tadalafil is just as effective as brand-name Cialis for treating erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). A 2023 trial in the American Journal of Urology found that 89% of men taking generic this ED pill experienced significant improvement, closely matching the 90% success rate of Lilly’s ED pill. Another study in the Journal of Sexual Medicine analyzed over 15,000 users and found no significant difference in onset time, duration of effect, or overall satisfaction between the generic and brand-name versions. With both meeting strict regulatory standards, the generic weekend pill remains a cost-effective alternative that delivers the same clinical benefits without the premium price tag.

Do you need a prescription for tadalafil?

Yes, tadalafil requires a prescription because it affects blood flow and blood pressure, making medical supervision essential. Doctors check for heart conditions, medication interactions, and other health risks before prescribing it. Taking it without medical advice can lead to serious side effects, especially if combined with nitrates or blood pressure drugs. While some websites sell this long-lasting libido booster without a prescription, these sources are often unsafe and may offer counterfeit pills. A doctor’s prescription ensures the right dosage and safety, and telehealth services provide a convenient way to get this ED drug from licensed pharmacies.

How long does tadalafil last? A comparison of different forms

Tadalafil is known for its long-lasting effects, staying active for up to 36 hours. Unlike Viagra, which lasts 4-6 hours, it offers more flexibility and spontaneity. Duration depends on dosage and frequency of use.

• 2.5 mg (Daily Use) – Stays in the body continuously, providing consistent readiness for men with mild ED or BPH.
• 5 mg (Daily Use) – Works the same as 2.5 mg, but at a stronger dose for men needing better results with daily use.
• 10 mg (As Needed) – Lasts up to 24 hours, making it a good option for occasional ED treatment.
• 20 mg (As Needed) – Effects last up to 36 hours, ideal for men who want more flexibility without strict timing.
• 40 mg (As Needed) – May last over 36 hours for those who need a stronger effect, but this dose increases the risk of side effects.

Some men report feeling the effects even after 48 hours, though intensity fades over time. Factors like metabolism, age, and food intake can influence how long this vascular relaxant lasts. A high-fat meal might slow absorption slightly, but it does not weaken the effect. With its long duration, the pill is perfect for those who want less planning and more spontaneity.

What are the key safety concerns?

Side effects

Tadalafil is designed for long-lasting effects, but some men may experience temporary side effects. The most common include headaches (15%), flushing (5%), and indigestion (6%). Unlike Viagra, this tablet rarely causes vision issues, though some report mild blurriness or light sensitivity. Muscle aches or back pain (up to 6%) can occur, often 12–24 hours after use, but usually fade within a day.

Serious side effects are rare but require immediate medical attention. Prolonged erections (priapism) lasting over four hours can cause permanent damage if untreated. Sudden hearing loss or ringing in the ears has been reported in rare cases, mainly in men with pre-existing ear conditions. A 2024 medical report found that only 2% of users experienced side effects lasting beyond 48 hours. Alcohol and certain medications can increase risks, so consulting a doctor about drug interactions is important.

Precautions and warnings

Tadalafil is not safe for everyone. Men with heart conditions, severe blood pressure issues, or a history of stroke should consult a doctor first, as it affects circulation. Taking it with nitrates, found in heart medications and poppers, can cause a dangerous blood pressure drop, leading to fainting or even a heart attack.

Men with kidney or liver disease may process the male enhancer more slowly, increasing the risk of headaches, dizziness, or prolonged erections. Rare cases of sudden vision or hearing loss have been reported, especially in those with pre-existing eye conditions. Drinking too much alcohol can worsen dizziness and low blood pressure, making the drug less effective. If you take alpha-blockers, antifungals, antibiotics, or HIV medications, speak with your doctor, as these can interact with the PDE5 inhibitor and increase side effect risks. Always use the recommended dose and avoid mixing it with unknown supplements.

How do I choose the right dosage?

Choosing the right erection tablet dosage depends on your health, lifestyle, and treatment goals. Doctors prescribe different strengths based on ED severity, frequency of use, and medical history. The wrong dose may lead to side effects or reduced effectiveness, so you need to understand your options.

Tadalafil Dosage Guide:

A low daily dose (2.5 mg or 5 mg) is great for spontaneity and BPH treatment, while higher doses (10 mg to 60 mg) are taken as needed. A doctor’s advice is crucial, especially for men with heart conditions or medication interactions. Always start with the lowest effective dose and adjust based on results.

What companies make generic Cialis?

Many companies make generic tadalafil, providing a cheaper alternative to the brand-name version. The first U.S. generic launched in 2018, and more manufacturers have since entered the market.

• Teva Pharmaceuticals – First to launch generic Cialis in the U.S. in 2018.
• Accord Healthcare, Ajanta Pharma, Alembic Pharmaceuticals, Amneal Pharmaceuticals, Aurobindo Pharma, Cipla, Dr. Reddy’s Laboratories, Hetero Labs, and Lupin – All received FDA approval in 2019.
• Other manufacturers – Macleods Pharmaceuticals, Prinston Pharmaceuticals, Qilu Pharmaceutical, Sun Pharmaceutical, Sunshine Lake Pharma, Torrent Pharmaceuticals, Umedica Laboratories, Unichem Laboratories, VKT Pharma, and Zydus Pharmaceuticals.

With FDA-approved manufacturers, this generic nedication meets high quality standards and is a safe, effective, and affordable alternative to the brand-name potency treatment.

Where to find real reviews for tadalafil?

In 2025, this tablet still remains one of the best options for treating erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). Many men share their experiences on trusted platforms, helping others decide if it’s the right choice. Reviews on Drugs.com rate tadalafil 8.5/10 based on 763 user experiences, with 81% of users sharing positive feedback about its effectiveness. Most praise its long-lasting effects, making it easier to be spontaneous without the need for precise timing. However, 10% mention side effects, with headaches and muscle pain being the most common complaints.

Ratings on WebMD show that over 90 users have shared their experiences, providing real feedback on the drug’s effectiveness and side effects. Around 85% rate it positively, highlighting stronger erections, improved confidence, and relief from urinary symptoms linked to BPH. Some users dislike mild issues like flushing or nasal congestion, but overall, this enhanced erection formula remains a popular and highly effective choice for many. Checking reliable sources with real user experiences can help make an informed decision before starting treatment.

How much does generic Cialis cost?

The price of generic tadalafil varies based on dosage, pharmacy, and insurance coverage. Without insurance, prices range from $8 to $42 per pill, depending on where you buy it. GoodRx lists prices between $8.53 and $29.99, while online providers like Ro and Hims offer tadalafil between $8 and $41 per pill. However, some online pharmacies sell it for as low as $0.50 per pill when buying in bulk, making it a much cheaper option. Choosing a lower daily dose or purchasing larger quantities can help reduce overall costs.

For those with insurance, the cost depends on your plan and copay structure. Some insurance plans charge the same price for all strengths, while others adjust costs based on dosage and frequency of use. Taking the pill daily or as needed can also impact the total expense. Prices vary by pharmacy, so comparing options and checking for discount programs, manufacturer coupons, or online deals can help you find the best price.

How to get maximum effect from Cialis?

The tablet works best when taken correctly and with the right lifestyle choices. Many men don’t get the full benefit because of timing, food, or unrealistic expectations. To ensure maximum effectiveness, follow these key steps:

• Take it at the right time – The best time to take Cialis is at least 30 minutes before activity, giving it enough time to work properly.
• Avoid heavy or fatty meals – A high-fat meal can slow absorption, making the medication take longer to work.
• Ensure natural arousal – This drug helps with blood flow, but sexual stimulation is still necessary for an erection.
• Choose the right dose – Some men need daily low doses (2.5 mg or 5 mg), while others benefit more from higher as-needed doses.
• Watch for drug interactions – Avoid nitrates, certain blood pressure medications, and excessive alcohol, which can lower blood pressure dangerously.
• Know possible side effects – Mild headache, flushing, or dizziness can happen. Severe effects like prolonged erections need medical attention.
• Maintain a healthy lifestyle – Exercise, eat well, and manage stress to naturally improve blood flow and enhance the drug’s effectiveness.

What are the side effects of sildenafil vs. tadalafil?

Sildenafil and tadalafil both treat erectile dysfunction (ED) but cause different side effects. Sildenafil, a shorter-acting option, is more likely to trigger headaches, flushing, and vision changes. Tadalafil stays in the body longer, increasing the chance of muscle and back pain. While most side effects are mild, some may require medical attention, especially for those with underlying health conditions.

Side Effect Comparison: Sildenafil vs. Tadalafil

As seen in the table, each drug’s side effects impact preference. Sildenafil’s shorter duration means its effects fade faster, while the other option lasts longer, sometimes prolonging discomfort like muscle aches. Some prefer a shorter-acting option with fewer muscle-related issues, while others value longer effectiveness despite the trade-off.

How to identify and avoid counterfeit medications?

Counterfeit tadalafil is a serious issue, with over 50% of online purchases potentially fake. These pills may contain incorrect ingredients, causing unexpected side effects or no effect. Some even have harmful substances that pose health risks. Here’s how to spot counterfeit pills:

• Examine the pill’s appearance – Authentic Cialis tablets are yellow, almond-shaped, and have “C” followed by the dosage number imprinted. If pills look cracked, crumbly, or have unusual coatings, they may be counterfeit.
• Check the packaging – Fake medication often comes in boxes with spelling errors, faded printing, or missing batch numbers. Official products have clear branding and a sealed blister pack.
• Avoid unusually low prices – If a pill is significantly cheaper than usual, it’s likely fake. Counterfeiters use discounts to trick buyers.
• Buy only from licensed pharmacies – Many illegal online sellers offer counterfeit ED pills. Look for the VIPPS (Verified Internet Pharmacy Practice Sites) seal when purchasing online.
• Verify the expiration date – Fake libido boosters may have missing, altered, or expired dates, which can indicate poor-quality or unsafe ingredients.

What are the best ways to save money on tadalafil?

This advanced ED solution can be expensive, but there are ways to cut costs without compromising on quality. Many overpay by not exploring cheaper options. Whether insured or paying out-of-pocket, choosing the right pharmacy, discounts, and prescription plans helps cut costs. Here are smart ways to get tadalafil affordably and safely:

• Check your insurance coverage – Some Medicare and private plans cover this potency aid. Contact your insurer or pharmacist to find out your options.
• Use a savings card – If your insurance doesn’t cover this ED pill, savings programs or pharmacy discount cards can lower the price.
• Choose generic tadalafil – Generic versions cost 60-80% less than brand-name medication but contain the same active ingredient.
• Buy a 90-day supply – Ordering in bulk can reduce per-pill costs and minimize pharmacy trips. Many insurance plans offer discounts for larger quantities.
• Consider online pharmacies – Licensed online pharmacies often have lower prices and deliver directly to your home, saving both money and time.
• Use manufacturer or pharmacy coupons – Search for promo codes and discounts from pharmacies or drug manufacturers before buying.
• Look into assistance programs – Organizations like NeedyMeds and the Medicine Assistance Tool offer financial help for those struggling to afford their prescriptions.

Where can I find more information about this drug?

For a detailed understanding of this oral ED treatment, including its uses, dosage, possible side effects, and more, explore the information provided here. This comprehensive guide explains how the medication works and what to expect. However, consulting a healthcare professional is crucial for personalized advice and safe use.

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Disclaimer: This content is for educational purposes only and not a substitute for medical advice. Always consult a healthcare professional before changing your medication or treatment. If you have health concerns, seek medical guidance promptly.